David Zucker

2 weeks ago | tvmovie.de | David Zucker |Anna Faris |Regina Hall |Craig Bierko

Heute20:15 - 21:5095 min. RTL II16:9TippUSA2006HorrorkomödieFilmparodien sind immer wieder zum Kaputtlachen! Besonders, wenn Komödienspezialist David Zucker persönlich die Regie übernimmt. Der zieht aber nicht nur Horrorfilme durch den Kakao. So steigt Scary Movie“-Dauerheldin Cindy (Anna Faris) als „Million Dollar Baby“ in den Boxring und schlägt sich mit riesigen „Krieg der Welten“-Aliens, einem kleinen Hausgeist im „The Grudge“-Stil und den tumben Bewohnern von „The Village“ herum.

Sep 23, 2024 | funnyhow.substack.com | Matt Ruby |David Zucker

You just taped a stand up special - now what? We recommend aiming for driving awareness of the special (e.g., with goals of x mentions in social media from fellow comedians, y appearances on podcasts and z streams of the special) and actual ticket sales (e.g., selling 50% of available tickets within the first month of launch). Think about how you will reach both existing and new fans - do you have an email list you can use for blasts or as seed audiences for ads?

Jun 1, 2024 | ranker.com | David Zucker |Jason Bancroft

David Zucker is a name synonymous with slapstick comedy and outrageous humor. As one of the creative minds behind classics like Airplane! and the Naked Gun series, his films have left audiences in stitches for decades. His unique style blends absurdity with sharp wit, making each movie a memorable ride of laughter. This list rounds up the best movies directed by David Zucker, showcasing his talent for turning even the most serious scenes into moments of comedic gold.

May 15, 2024 | nature.com | Xue Sun |Atif Ahmed Siddiqui |Georgi K. Marinov |Sagiv Shifman |David Zucker |Adi Oron-Gottesman | +7 more

Classical evolutionary theories propose tradeoffs among reproduction, damage repair and lifespan. However, the specific role of the germline in shaping vertebrate aging remains largely unknown. In this study, we used the turquoise killifish (Nothobranchius furzeri) to genetically arrest germline development at discrete stages and examine how different modes of infertility impact life history. We first constructed a comprehensive single-cell gonadal atlas, providing cell-type-specific markers for downstream phenotypic analysis. We show here that germline depletion—but not arresting germline differentiation—enhances damage repair in female killifish. Conversely, germline-depleted males instead showed an extension in lifespan and rejuvenated metabolic functions. Through further transcriptomic analysis, we highlight enrichment of pro-longevity pathways and genes in germline-depleted male killifish and demonstrate functional conservation of how these factors may regulate longevity in germline-depleted Caenorhabditis elegans. Our results, therefore, demonstrate that different germline manipulation paradigms can yield pronounced sexually dimorphic phenotypes, implying alternative responses to classical evolutionary tradeoffs. Moses, Atlan et al. profile the killifish (Nothobranchius furzeri) gonad using single-cell sequencing and reveal that genetic germline depletion induces sexually dimorphic phenotypes, enhancing lifespan in male fish and somatic repair in females.

Apr 24, 2024 | funnyhow.substack.com | Matt Ruby |David Zucker

is a NYC digital marketing consultant and a former analyst at TikTok. He uses a data-driven approach to advise entertainers and has a mailing list that offers advice. Here’s a recent entry: The Secret to a Viral Comedy Clip. Your goal should not be to get a million views. If you are a comedian posting on social media, your goal should be to get your clip sent in a group chat full of people you don’t know…True virality, and in turn, fandom, rarely starts with a paid ad.