de la Iglesia

2 weeks ago | academic.oup.com | Universitat de Barcelona |de la Iglesia |Juan Manuel |Andrology Unit

Protamines are considered among the most relevant sperm proteins because of their functional implications on paternal genome packaging and protection. Although the proteomic evaluation of protamines is technically challenging, mass spectrometry-based studies have shown a complex population of protamine proteoforms in the human sperm. This included intact, truncated and modified forms for protamine 1 (P1) and mature and immature components of protamine 2 family (P2).