Diana Spencer

1 week ago | ddw-online.com | Diana Spencer

Scientists in the UK and Belgium have discovered new insights into how four different anti-amyloid drugs interact with amyloid beta protein, revealing why the drugs have had varying levels of success at treating Alzheimer’s disease. Amyloid beta is one of the toxic proteins which builds up in clumps or ‘aggregates’ in the brains of people affected by Alzheimer’s. Several drugs targeting the protein have been tested in trials over recent years.

1 week ago | ddw-online.com | Diana Spencer

A new study from researchers at Lund University in Sweden and Imperial College London suggests that treating patients earlier with a combination of statins and the cholesterol-lowering drug ezetimibe could prevent thousands of new heart attacks. For those who survive a heart attack, the risk of a new heart attack is greatest in the first year after the initial event. The current treatment guidelines for patients are high-potency statins immediately after a heart attack.

1 week ago | ddw-online.com | Diana Spencer

Scientists at the Wellcome Sanger Institute in collaboration with Pacific Biosciences (PacBio) have launched a new initiative to map how gene activity shapes the immune system. It is hoped that the project will identify new therapeutic targets for conditions such as inflammatory bowel disease (IBD).

1 week ago | ddw-online.com | Diana Spencer

DDW Editor Reece Armstrong looks at how advances in stem cells, organoids and 3D cell cultures are affecting drug discovery and development. Stem cells, organoids and 3D cell cultures have emerged as promising tools that scientists can use to better understand disease and how drugs function within the human body.

1 week ago | ddw-online.com | Diana Spencer

Hosted by Drug Discovery World and sponsored by The Jackson Laboratory, register now for the DDW ‘Turning Science into Business’ AI & ML summit: Navigating AI-driven drug discovery, to learn about the areas of opportunity for AI & ML in the drug discovery sector. Taking place on 30 April, 7am PDT / 10am EDT / 3pm BST / 4pm CEST, this free event will see experts and thought leaders in AI describe the latest research and applications that are driving the drug discovery process.