Difei Tong

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Exposurea to Polystyrene Nanoplastics Led to Learning And Memory Deficits in Zebrafish by Inducing Oxidative Damage And Aggravating Brain Aging

Aug 23, 2023 | pericles.pericles-prod.literatumonline.com | Weishang Zhou |Dandan Tian |Yingying Yu |Difei Tong

Nanoplastics (NPs) may pass through the blood-brain barrier, giving rise to serious concerns about their potential toxicity to the brain. In this study, the effects of NPs exposure on learning and memory, the primary cognitive functions of the brain, were assessed in zebrafish with classic T-maze exploration tasks. Additionally, to reveal potential affecting mechanisms, the impacts of NPs exposure on brain aging, oxidative damage, energy provision, and the cell cycle were evaluated.

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