Dilip Mehta

3 weeks ago | scienceopen.com | Nidhi Thakkar |Gemini Gajera |Dilip Mehta |Sujit Nair

The nematode Caenorhabditis elegans is an important model for studying the genetics of ageing, with over 50 life-extension mutations known so far. However, little is known about the pathobiology of ageing in this species, limiting attempts to connect genotype with senescent phenotype. Using ultrastructural analysis and visualization of specific cell types with green fluorescent protein, we examined cell integrity in different tissues as the animal ages.

Aug 2, 2024 | biorxiv.org | Nidhi Thakkar |Gemini Gajera |Dilip Mehta |Sujit Nair

AbstractWithania somnifera is among the most widely prescribed medicinal plants in traditional Indian medicine. Hydroalcoholic extract of the roots of this plant was investigated for its effects on the overall health and lifespan of the model worm Caenorhabditis elegans. Extract-exposed worms registered longer lifespan, higher fertility, better motility and metabolic activity.

Aug 2, 2024 | biorxiv.org | Nidhi Thakkar |Gemini Gajera |Dilip Mehta |Sujit Nair

AbstractWithania somnifera is among the most widely prescribed medicinal plants in traditional Indian medicine. Hydroalcoholic extract of the roots of this plant was investigated for its effects on the overall health and lifespan of the model worm Caenorhabditis elegans. Extract-exposed worms registered longer lifespan, higher fertility, better motility and metabolic activity.