Domenico Cozzetto

Nov 19, 2024 | cell.com | Jana Obajdin |Daniel Larcombe-Young |Maya Glover |Caroline Hull |Katie Flaherty |Ge Tan | +13 more

Keywordschimeric antigen receptorNKG2DDap10Dap12adaptorIntroductionNKG2D is expressed by natural killer (NK) cells, CD8+ αβ T cells, γδ T cells, invariant NKT cells, and some CD4+ T cell subsets.1 It mediates the recognition of cells that express any of the eight NKG2D ligands (NKG2DLs), namely MHC class I polypeptide-related sequence (MIC)A/B and UL16-binding protein (ULBP)1–6.

Sep 7, 2023 | nature.com | Niclas Eriksson |Erin Macdonald-Dunlop |Stefan Enroth |Domenico Cozzetto |Lasse Folkersen |Christian Herder | +16 more

Correction to: Nature Immunology https://doi.org/10.1038/s41590-023-01588-w, published online 10 August 2023. In the version of the article originally published, the middle panel in Fig. 3b was mistakenly a duplicate of the upper panel. The figure has now been corrected in the HTML and PDF versions of the article.

Aug 10, 2023 | nature.com | Niclas Eriksson |Erin Macdonald-Dunlop |Stefan Enroth |Domenico Cozzetto |Lasse Folkersen |Christian Herder | +16 more

AbstractCirculating proteins have important functions in inflammation and a broad range of diseases. To identify genetic influences on inflammation-related proteins, we conducted a genome-wide protein quantitative trait locus (pQTL) study of 91 plasma proteins measured using the Olink Target platform in 14,824 participants. We identified 180 pQTLs (59 cis, 121 trans).