Dominique Hancock

Nov 28, 2024 | cell.com | Alejandra Raudales |Ben Schager |Dominique Hancock |Sorabh Sharma |Patrick Reeson |Manjinder S. Cheema | +4 more

KeywordsangiogenesismicrocirculationplasticityNotchVEGFrarefactioncapillaryblood flowResearch topic(s)CP: NeuroscienceCP: Molecular biologyIntroductionThe brain uses up to 20% of the energy metabolized by the body to sustain its needs.1 Despite these demands, there is little capacity for energy storage in the form of glycogen; therefore, the brain requires a constant supply of blood.

May 26, 2024 | biorxiv.org | Sorabh Sharma |Alejandra Raudales |Ben Schager |Dominique Hancock

AbstractCerebral angiogenesis is well appreciated in development and after injury, but the extent to which it occurs across cortical regions in normal adult mice and underlying mechanisms, is incompletely understood. Using in vivo imaging, we show that angiogenesis in anterior-medial cortical regions (retrosplenial and sensorimotor cortex), was exceptionally rare.