Dongwon Lee

Jan 24, 2025 | digitalcommons.library.tmc.edu | Dongwon Lee |Wu Chen |Heet Naresh Kaku |Xinming Zhuo

UBE3A encodes ubiquitin protein ligase E3A, and in neurons its expression from the paternal allele is repressed by the UBE3A antisense transcript (UBE3A-ATS). This leaves neurons susceptible to loss-of-function of maternal UBE3A. Indeed, Angelman syndrome, a severe neurodevelopmental disorder, is caused by maternal UBE3A deficiency. A promising therapeutic approach to treating Angelman syndrome is to reactivate the intact paternal UBE3A by suppressing UBE3A-ATS.

Jun 8, 2023 | arxiv.org | Dongwon Lee |Andreas Vlachos

With the explosive advancement of AI technologies in recent years, the scene of the disinformation research is also expected to rapidly change. In this viewpoint article, in particular, we first present the notion of "disinformation 2.0" in the age of AI where disinformation would become more targeted and personalized, its content becomes very difficult to distinguish from real news, and its creation and dissemination become more accelerated by AI.