Drew Neavin

May 13, 2024 | nature.com | Nona Farbehi |Drew Neavin |Lorenz Studer

AbstractHuman pluripotent stem (hPS) cells can, in theory, be differentiated into any cell type, making them a powerful in vitro model for human biology. Recent technological advances have facilitated large-scale hPS cell studies that allow investigation of the genetic regulation of molecular phenotypes and their contribution to high-order phenotypes such as human disease.

Feb 23, 2023 | genomebiology.biomedcentral.com | Angli Xue |Seyhan Yazar |Drew Neavin |Joseph Powell

Three single-cell datasets were used in this study to explore the performance of the PEER and PCA methods. The OneK1K consortium [14] is a population-scale single-cell RNA-seq dataset collected in Tasmania, Australia. This cohort includes 982 individuals, each with gene expression profiling for ~ 1000 (mean = 1297.0, standard deviation = 23.6) peripheral blood mononuclear cells (PBMCs).