Dustin Heiden

1 month ago | biorxiv.org | Jennifer Berger |Alayna M. Rosales |Brendan Monogue |Dustin Heiden

AbstractThe central nervous system (CNS) includes a uniquely regulated immune response that supports homeostasis, response to injury, and response to pathogens. Recent work has shown that virus-associated immune responses in the CNS may contribute to neuronal injury and long term outcomes such as neurocognitive decline. However, the fundamental mechanisms that regulate acute infiltration of immune cells from vascular compartments into the CNS are not well defined.