Dustin S Siegel

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Discovery and Synthesis of GS-7682, a Novel Prodrug of a 4'-CN-4-Aza-7,9-Dideazaadenosine C-Nucleoside with Broad-Spectrum Potency Against Pneumo- and Picornaviruses and Efficacy in RSV-Infected African Green Monkeys.

Apr 19, 2024 | biorxiv.org | Dustin S Siegel |Jared D. Pitts |Meghan S. Vermillion |C. Hui

AbstractAcute respiratory viral infections (ARVI), such as pneumovirus and respiratory picornavirus infections, exacerbate disease in COPD and asthma patients.
Discovery of GS-7682, a Novel 4′-Cyano-Modified C-Nucleoside Prodrug with Broad Activity against Pneumo- and Picornaviruses and Efficacy in RSV-Infected African Green Monkeys

Apr 16, 2024 | dx.doi.org | Dustin S Siegel |C. Hui |Jared D. Pitts |Meghan S. Vermillion
Discovery of GS-7682, a Novel 4′-Cyano-Modified C-Nucleoside Prodrug with Broad Activity against Pneumo- and Picornaviruses and Efficacy in RSV-Infected African Green Monkeys

Apr 16, 2024 | pubs.acs.org | Dustin S Siegel |C. Hui |Jared D. Pitts |Meghan S. Vermillion

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