Eduardo Martin Moraud

Nov 6, 2023 | nature.com | Tomislav Milekovic |Eduardo Martin Moraud |Charlotte Moerman |Shiqi Sun |Matthew G. Perich |Robin Demesmaeker | +17 more

AbstractPeople with late-stage Parkinson’s disease (PD) often suffer from debilitating locomotor deficits that are resistant to currently available therapies. To alleviate these deficits, we developed a neuroprosthesis operating in closed loop that targets the dorsal root entry zones innervating lumbosacral segments to reproduce the natural spatiotemporal activation of the lumbosacral spinal cord during walking.