Eduardo Sandoval

Dec 20, 2023 | nature.com | Colin Hoy |Eduardo Sandoval |Peter Weber

AbstractThe signed value and unsigned salience of reward prediction errors (RPEs) are critical to understanding reinforcement learning (RL) and cognitive control. Dorsomedial prefrontal cortex (dMPFC) and insula (INS) are key regions for integrating reward and surprise information, but conflicting evidence for both signed and unsigned activity has led to multiple proposals for the nature of RPE representations in these brain areas.