Elin Madli Peets

Jan 14, 2025 | biorxiv.org | Jonas Koeppel |Pierre Murat |Gareth Girling |Elin Madli Peets

AbstractHuman gene expression is controlled from distance via enhancers, which can form longer "super-enhancer"-regions of intense regulatory activity. Whether super-enhancers constitute a separate regulatory paradigm remains unclear, largely due to the difficulty of dissecting the contributions and interactions of individual elements within their natural chromosomal context.