Enrique Rodriguez

1 month ago | biorxiv.org | Ekin Daplan |Enrique Rodriguez |Nick Lane |Luca Turin

AbstractIt has long been known that phosgene, a war gas and an industrial reagent, causes intense oxidative stress, but how it does so remains unclear. Here we report an accidental discovery: Electron spin resonance spectroscopy (ESR) of live fruit flies reveals that phosgene exposure results in a distinctive manganese (Ⅱ) hyperfine structure. After exposure to phosgene, every batch of flies consistently displays the Mn (Ⅱ) signal.