Eric P. Plaisance

Nov 11, 2024 | onlinelibrary.wiley.com | Katie Ellison |Kimberly Smith |Jose Fernandez |José Fernandez |José Fernández |Eric P. Plaisance

1 Introduction Obesity is one of the most detrimental diseases routinely seen in primary care and there is clear evidence that it is causally related to heart disease, type 2 diabetes, stroke, and some cancers [1]. Weight loss of 5% is generally accepted as the minimum threshold for clinical significance, but the American Association of Clinical Endocrinologists (AACE) and American College of Endocrinology (ACE) recommend 10%–15% weight loss for those with comorbid conditions [2].