Erica K. Barnell

Apr 1, 2024 | jamanetwork.com | Erica K. Barnell |David Lieberman |Elizabeth M. Wurtzler |Julie La Rocca

Multitarget Stool RNA Testing—Reply Multitarget Stool RNA Test for Colorectal Cancer Screening Erica K. Barnell, MD, PhD; Elizabeth M. Wurtzler, PhD; Julie La Rocca, MS; Thomas Fitzgerald, MS; Jessica Petrone, MD; Yansheng Hao, MD, PhD; Yiming Kang, PhD; Faith L. Holmes, MD; David A. Lieberman, MD Multitarget Stool RNA Testing Multitarget Stool RNA Testing Thomas F. Imperiale, MD; Philip Lavin, PhD; David F.

Oct 23, 2023 | jamanetwork.com | Erica K. Barnell |Elizabeth M. Wurtzler |Julie La Rocca |Thomas Fitzgerald

Key PointsQuestion  What is the performance of the novel multitarget stool RNA (mt-sRNA) test (ColoSense) for individuals 45 years and older undergoing colorectal cancer screening? Findings  A pivotal prospective, cross-sectional clinical trial comprising 8920 eligible participants was used to evaluate the sensitivity and specificity of the mt-sRNA test compared with a colonoscopy.