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Sep 29, 2023 | 
sciencemag.org | Jens C. Brüning |Joana I. Meier |Erik D Enbody |Ashley T. Sendell-Price
Supplementary MaterialsMaterials and MethodsSupplementary Notes S1 to S5Figs. S1 to S26Tables S5 and S6References and Notes1G. G. Simpson, Tempo and Mode in Evolution (Columbia Univ. Press, 1944). 2A. R. Evans, D. Jones, A. G. Boyer, J. H. Brown, D. P. Costa, S. K. M. Ernest, E. M. G. Fitzgerald, M. Fortelius, J. L. Gittleman, M. J. Hamilton, L. E. Harding, K. Lintulaakso, S. K. Lyons, J. G. Okie, J. J. Saarinen, R. M. Sibly, F. A. Smith, P. R. Stephens, J. M. Theodor, M. D. Uhen, The maximum rate of mammal evolution. Proc. Natl. Acad. Sci.
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Sep 28, 2023 | 
science.org | Jens C. Brüning |Joana I. Meier |Erik D Enbody |Ashley T. Sendell-Price
Supplementary MaterialsMaterials and MethodsSupplementary Notes S1 to S5Figs. S1 to S26Tables S5 and S6References and Notes1G. G. Simpson, Tempo and Mode in Evolution (Columbia Univ. Press, 1944). 2A. R. Evans, D. Jones, A. G. Boyer, J. H. Brown, D. P. Costa, S. K. M. Ernest, E. M. G. Fitzgerald, M. Fortelius, J. L. Gittleman, M. J. Hamilton, L. E. Harding, K. Lintulaakso, S. K. Lyons, J. G. Okie, J. J. Saarinen, R. M. Sibly, F. A. Smith, P. R. Stephens, J. M. Theodor, M. D. Uhen, The maximum rate of mammal evolution. Proc. Natl. Acad. Sci.
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Sep 28, 2023 | 
science.org | Jens C. Brüning |Joana I. Meier |Erik D Enbody |Yijie Wang
Published In ScienceVolume 381 | Issue 666529 September 2023Article versionsSubmission historyReceived: 27 March 2023Accepted: 11 August 2023Published in print: 29 September 2023PermissionsRequest permissions for this article. AcknowledgmentsWe thank E. Olson (University of Texas Southwestern) for sharing the TCF21MCM mice with us. We thank G. Salama (University of Pittsburgh) for assisting with ephaptic experiments. We thank the following colleagues from UCLA: K. Shivkumar and P.
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Sep 28, 2023 | 
science.org | Jens C. Brüning |Joana I. Meier |Erik D Enbody |Shao-Feng Liu
Published In ScienceVolume 381 | Issue 666529 September 2023Article versionsSubmission historyReceived: 13 January 2023Accepted: 9 August 2023Published in print: 29 September 2023PermissionsRequest permissions for this article. AcknowledgmentsWe thank TCL Inc. China for providing QDs (red CdZnSe/CdZnS/ZnS and green CdZnSe/ZnSe/ZnS); Y. Zhao and H. Fan (Tsinghua University) for designing the 3D chiral model and writing the program; X.
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Sep 28, 2023 | 
science.org | Jens C. Brüning |Joana I. Meier |Erik D Enbody |Becky Ham
Association AffairsIn 2022, the American Association for the Advancement of Science unveiled a new strategic vision with four focused and refined goals, which will guide the organization for years to come. They include advancing scientific excellence and achievement; fostering equity and inclusion for scientific excellence; building trust among scientists and communities; and catalyzing progress where science meets policy.
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Sep 28, 2023 | 
science.org | Jens C. Brüning |Joana I. Meier |Erik D Enbody |Mattia Maroso
Neurodegeneration Eating up synapsesMattia MarosoIn individuals with Alzheimer’s disease (AD), synapse loss correlates with cognitive decline. Investigating how synapses are lost during AD, Tzioras et al. found that astrocytes and microglia showed increased amounts of synaptic proteins in AD brains and in synaptoneurosomes derived from AD brains. This finding indicates that elevated synapse phagocytosis occurs during AD.
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Sep 28, 2023 | 
science.org | Jens C. Brüning |Joana I. Meier |Erik D Enbody |Tyler J. Pearson
Published In ScienceVolume 381 | Issue 666529 September 2023Article versionsSubmission historyReceived: 1 July 2023Accepted: 28 August 2023Published in print: 29 September 2023PermissionsRequest permissions for this article. AcknowledgmentsWe thank S. Snyder (UChicago) for helpful discussions. We thank P. Kelly (UChicago) for assistance with separations. The University of Chicago’s Research Computing Center is thanked for computational resources.
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Sep 28, 2023 | 
science.org | Jens C. Brüning |Joana I. Meier |Erik D Enbody |Kai Kupferschmidt
It came as a nasty surprise when Candida auris suddenly started to cause deadly infections in 2011. The yeast was resistant to major classes of drugs and killed more than one-third of known patients who developed invasive infections. Even more surprising, C. auris infections had apparently emerged simultaneously around the world. “There was just no good explanation,” says Arturo Casadevall, a microbiologist at the Johns Hopkins Bloomberg School of Public Health.
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Sep 28, 2023 | 
science.org | Jens C. Brüning |Joana I. Meier |Erik D Enbody |Jon Cohen
Just as viruses wash back and forth between species, so do genes that enable bacteria to shrug off antibiotics. Arising in people and livestock that are heavily dosed with the drugs, bacteria that evolve antimicrobial resistance (AMR) are spread far and wide by birds. “In this part of the world, it's definitely the gulls,” says Jonas Bonnedahl, an infectious disease clinician based at Linköping University in Sweden.
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Sep 28, 2023 | 
science.org | Jens C. Brüning |Joana I. Meier |Erik D Enbody |Kai Kupferschmidt
When the World Health Organization called attention in 2022 to a surge in cholera outbreaks around the globe, it listed the usual factors that favor waterborne diseases: lack of sanitation, humanitarian crises, and conflict. But it also said climate change was worsening the situation. Cholera is caused by Vibrio cholerae, a bacterium that can produce a toxin and spreads when the stool of infected people contaminates drinking water and food.
