Eva Polverino

Oct 22, 2024 | emjreviews.com | Eva Polverino |Marc Miravitlles |Luca Richeldi |Franziska Trudzinski

Clinical Aspects and Diagnosis of BronchiectasisBronchiectasis is a clinical condition defined as a chronic, abnormal dilation of the bronchi accompanied by classical symptoms.1,2 While the disease typically develops from chronic airway inflammation and/or infection, it has multiple aetiologies (excluding cystic fibrosis, which is considered a separate clinical entity) that can be associated with several different conditions (Figure 1).1,3Figure 1: Major known causes of bronchiectasis.

Oct 9, 2024 | err.ersjournals.com | Visser SK |Fox GJ |Eva Polverino

IntroductionBronchiectasis is a chronic respiratory disease characterised by permanent bronchial dilatation evidenced at chest computed tomography (CT), associated with a clinical syndrome featuring daily cough, daily sputum production and a history of pulmonary exacerbations [1]. In the last few decades, bronchiectasis has rapidly moved from being a rare or orphan disease to a global problem, with a large-scale trend towards increasing incidence and prevalence [2].

Jun 6, 2024 | erj.ersjournals.com | Stefano Aliberti |Eva Polverino |Charles S. Haworth |Michael R Loebinger

IntroductionImpaired mucociliary clearance is one of the defining features of the clinical syndrome of bronchiectasis [1, 2]. The most frequent symptoms that impact upon patients’ quality of life are cough and sputum production, commonly characterised by secretions with high viscoelasticity [3–5].

Apr 24, 2023 | thelancet.com | James Chalmers |Eva Polverino |Megan L. Crichton |Felix C. Ringshausen

Having observed that patients in central and eastern Europe were more likely to have severe cystic bronchiectasis and were less likely to receive evidence-based treatments, we investigated whether this translated into more exacerbations during follow-up. For this analysis of regional differences in exacerbations, we included 9978 patients who had at least 1 year of follow-up data.