F. Christian Bennett

Sep 13, 2023 | nature.com | Sebastien Tremblay |Sébastien Tremblay |Ilyas Singeç |Clifford J. Woolf |Matthew Hayes |F. Christian Bennett | +4 more

AbstractWith concurrent global epidemics of chronic pain and opioid use disorders, there is a critical need to identify, target and manipulate specific cell populations expressing the mu-opioid receptor (MOR). However, available tools and transgenic models for gaining long-term genetic access to MOR+ neural cell types and circuits involved in modulating pain, analgesia and addiction across species are limited.