Falk Libby E

Jun 12, 2023 | onlinelibrary.wiley.com | Peter Middleton |Nicholas Simmonds |Falk Libby E

Abstract Bronchiectasis is often considered progressive and irreversible, so cases of regression or reversal are an important step in understanding the underlying pathophysiological mechanisms. Cystic fibrosis, (CF) caused by pathogenic variants in the cystic fibrosis transmembrane conductance regulator (CFTR) gene has been a success story in personalized medicine. The recent development of CFTR modulator therapies has revolutionized care.