Farzan Ghanegolmohammadi

Feb 4, 2025 | biorxiv.org | Shane Byrne |Evan Davis |Rahul Raman |Farzan Ghanegolmohammadi

AbstractArginine, glutamic acid and selenocysteine based codon bias has been shown to regulate the translation of specific mRNAs for proteins that participate in stress responses, cell cycle and transcriptional regulation. Defining codon-bias in gene networks has the potential to identify other pathways under translational control.

Nov 3, 2024 | biorxiv.org | Shane Byrne |Shinsuke Ohnuki |Thomas Begley |Farzan Ghanegolmohammadi

AbstractBackground: The degeneracy of the genetic code is increasingly recognized for roles in regulating translation rate, protein folding, and cell response. However, the functional genomics of codon usage patterns remains poorly defined.