Feng Hu

May 7, 2024 | mdpi.com | YiQuan Zou |Feng Hu |Jie Cai |Han Pan

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Apr 8, 2024 | nature.com | Grace Goodhart |Julien Dilly |Nicole Nasholm |Tamar Ziv |Jennifer Roth |Matthew Rees | +9 more

AbstractRAS oncogenes (collectively NRAS, HRAS and especially KRAS) are among the most frequently mutated genes in cancer, with common driver mutations occurring at codons 12, 13 and 611. Small molecule inhibitors of the KRAS(G12C) oncoprotein have demonstrated clinical efficacy in patients with multiple cancer types and have led to regulatory approvals for the treatment of non-small cell lung cancer2,3.

Mar 11, 2024 | cell.com | Feng Hu |Piro Lito

The histologic transformation of adenocarcinoma (ADC) to squamous cell carcinoma (SCC), known as adeno-squamous transition or AST, is frequently observed in patients with lung cancer undergoing cancer therapy. In this issue, Tong and colleagues investigate genetic and epigenetic mechanisms that drive AST to confer resistance to KRAS inhibitors in preclinical models and patients.

Dec 18, 2023 | dx.doi.org | Yuting Li |Chen Yang |Feng Hu |Hui Hu

RETURN TO ARTICLES ASAPPREVBiological and Medic...Biological and Medical Applications of Materials and InterfacesNEXT Yuting Li School of Resource and Environmental Science, Hubei Engineering Center of Natural Polymers-Based Medical Materials, Hubei Biomass-Resource Chemistry and Environmental Biotechnology Key Laboratory, Hubei International Scientific and Technological Cooperation Base of Sustainable Resource and Energy, Wuhan University, Wuhan 430079, China , Chen Yang School of Resource...

Nov 10, 2023 | ascelibrary.org | Feng Hu

To solve the problem using the Lagrange algorithm can result in severe distortions in large deformation calculations and the Euler algorithm cannot describe the material interface accurately; therefore, Ramaswamy and Kawahara (1987) and Hureta and Liu (1988) developed the multimaterial arbitrary Lagrange-Euler (ALE) algorithm. The ALE algorithm includes advantages of both Lagrange and Euler algorithms.