Fengjuan Zhang

Nov 26, 2024 | mdpi.com | Xiaohui Zhan |Fengjuan Zhang |Ning Li |Kai Xu

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Aug 17, 2023 | nature.com | Fengjuan Zhang

AbstractCRISPR-Cas systems endow the bacterial and archaeal species with adaptive immune mechanisms to fend off invading phages and foreign plasmids. The class 2 type VI CRISPR/Cas effector Cas13d has been harnessed to confer the protection against RNA viruses in diverse eukaryotic species. However a vast number of different viruses can potentially infect the same host plant resulting in mixed infection, thus necessitating the generation of crops with broad-spectrum resistance to multiple viruses.