Fengming Chen

Dec 17, 2024 | mdpi.com | Fengming Chen

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Nov 3, 2024 | biorxiv.org | Matthew K Iyer |Ashley Fletcher |Chanjuan Shi |Fengming Chen

AbstractPurpose: Intraductal papillary mucinous neoplasms (IPMN) occur in 5-10% of the population, but only a small minority progress to pancreatic ductal adenocarcinoma (PDAC). The lack of accurate predictors of high-risk disease leads both to unnecessary operations for indolent neoplasms as well as missed diagnoses of PDAC. Digital spatial RNA profiling (DSP-RNA) provides an opportunity to define and associate transcriptomic states with cancer risk.