Fernando Cardes

Aug 21, 2024 | nature.com | Matteo Cartiglia |Shyam Narayanan |Hasan Uluşan |Andreas Hierlemann |Fernando Cardes

AbstractBio-signal sensing is pivotal in medical bioelectronics. Traditional methods focus on high sampling rates, leading to large amounts of irrelevant data and high energy consumption. We introduce a self-clocked microelectrode array (MEA) that digitizes bio-signals at the pixel level by encoding changes as asynchronous digital address-events only when they exceed a threshold, significantly reducing off-chip data transmission.

May 10, 2023 | pubmed.ncbi.nlm.nih.gov | Fernando Cardes |Ebrahim Azizi |Andreas Hierlemann

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Feb 13, 2023 | onlinelibrary.wiley.com | Wei Wei |Andreas Hierlemann |Fernando Cardes |Mario M. Modena

2.4 The BBB Platform as an Effective In Vitro Model for Recapitulating Ischemic Injuries After confirming that our system was capable of monitoring rapid variations in BBB permeability and EC-layer organization, we challenged our barrier model with an ischemia-like insult by exposing the model to oxygen glucose deprivation (OGD), which is a commonly applied method to induce ischemic injuries in vitro[64] (Figure 5a).