Fotis Christakopoulos

Oct 23, 2024 | dx.doi.org | Zefan Wang |Biying Li |Fotis Christakopoulos |Kefeng Xie

Sep 16, 2024 | biorxiv.org | Lucia G. Brunel |Chris Long |Fotis Christakopoulos |Betty Cai

AbstractHydrogels composed of collagen, the most abundant protein in the human body, are widely used as scaffolds for tissue engineering due to their ability to support cellular activity. However, collagen hydrogels with encapsulated cells often experience bulk contraction due to cell-generated forces, and conventional strategies to mitigate this undesired deformation often compromise either the fibrillar microstructure or cytocompatibility of the collagen.