Francesco Andreatta

Nov 27, 2024 | nature.com | Anais Elewaut |Felix Bayerl |Martin Schönlein |Trung Nguyen |Trung Nguyễn |Francesco Andreatta | +12 more

AbstractThe tumour microenvironment is programmed by cancer cells and substantially influences anti-tumour immune responses1,2. Within the tumour microenvironment, CD8+ T cells undergo full effector differentiation and acquire cytotoxic anti-tumour functions in specialized niches3,4,5,6,7. Although interactions with type 1 conventional dendritic cells have been implicated in this process3,4,5,8,9,10, the underlying cellular players and molecular mechanisms remain incompletely understood.

Nov 27, 2024 | nature.com | Anais Elewaut |Felix Bayerl |Martin Schönlein |Trung Nguyen |Trung Nguyễn |Francesco Andreatta | +12 more

AbstractThe tumour microenvironment is programmed by cancer cells and substantially influences anti-tumour immune responses1,2. Within the tumour microenvironment, CD8+ T cells undergo full effector differentiation and acquire cytotoxic anti-tumour functions in specialized niches3,4,5,6,7. Although interactions with type 1 conventional dendritic cells have been implicated in this process3,4,5,8,9,10, the underlying cellular players and molecular mechanisms remain incompletely understood.