Francesco Puppo

Dec 2, 2024 | mdpi.com | Francesco Puppo |Roberto G. Carbone

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Jul 12, 2023 | frontiersin.org | Quan Zou |Francesco Puppo |James Dunne

IntroductionSystemic sclerosis (scleroderma; SSc) is a heterogeneous connective tissue disease characterized by progressive cutaneous and visceral fibrosis (Denton and Khanna, 2017). The overall prevalence and incidence of SSc in global were 17.6 per 100, 000 and 1.4 per 100,000 person-years, respectively (Bairkdar et al., 2021).