Frank Porreca

Mar 13, 2024 | journals.sagepub.com | Frank Porreca |Edita Navratilova |Joe Hirman |Richard Lipton

Conclusion/InterpretationPublished data evaluating the acute treatment effects of gepant drugs from more than 2595 women and 422 men show significant effects on PF and MBS outcomes in women but the available data do not show significant effects in men. The magnitude of the TE observed was always larger in women than in men. Additionally, the calculated NNTs were higher for men than for women for all gepant studies.

Jul 24, 2023 | jamanetwork.com | Frank Porreca |Mayo Clinic Arizona |David W Dodick

Considering Patient Sex in Prescribing CGRP Receptor Antagonists for Short-Term Treatment of Migraine Migraine is the world’s most common neurological disorder, affecting approximately 1 billion people worldwide, the great majority of whom (approximately 700 million) are women. This female predominance is reflected in the clinic and in clinical trials, where most patients (~85%) are women.