Frédéric Lesage

2 months ago | nature.com | Sarah Fraser |Frédéric Lesage

AbstractAge-related arterial stiffness increases pulsatility that reaches the cerebral microcirculation, compromises cerebrovascular health and lead to cognitive decline. The presence of cardiovascular risk factors (CVRFs) such as high blood pressure can exacerbate this effect. Despite extensive research on the impact of antihypertensive treatments on reducing arterial stiffness, little is known about the impact of antihypertensive treatments on pulsatility in cerebral microcirculation.

May 22, 2024 | nature.com | Élodie Labrecque Langlais |Gemina Doolub |Sebastián Mrad |Jean-Claude Tardif |Guillaume Marquis-Gravel |Geoffrey H. Tison | +1 more

AbstractThe coronary angiogram is the gold standard for evaluating the severity of coronary artery disease stenoses. Presently, the assessment is conducted visually by cardiologists, a method that lacks standardization. This study introduces DeepCoro, a ground-breaking AI-driven pipeline that integrates advanced vessel tracking and a video-based Swin3D model that was trained and validated on a dataset comprised of 182,418 coronary angiography videos spanning 5 years.