Frederik Dalgaard

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Cardiac resynchronization therapy in patients with a prior history of atrial fibrillation: Insights from four major clinical trials

Jul 31, 2023 | onlinelibrary.wiley.com | Frederik Dalgaard |Marat Fudim |Sana M. Al-Khatib |Daniel Friedman

Abstract Aims To investigate the association of cardiac resynchronization therapy (CRT) on outcomes among participants with and without a history of atrial fibrillation (AF). Methods Individual-patient-data from four randomized trials investigating CRT-Defibrillators (COMPANION, MADIT-CRT, REVERSE) or CRT-Pacemakers (COMPANION, MIRACLE) were analyzed. Outcomes were time to a composite of heart failure hospitalization or all-cause mortality or to all-cause mortality alone.

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