Geoffrey Chupp

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Articles

Shared genetic architecture of blood eosinophil counts and asthma in UK Biobank

Jul 1, 2023 | openres.ersjournals.com | Shannon L Kay |Geoffrey Chupp

IntroductionEosinophils are leukocytes involved in type 2 (T2) immune responses against macroparasites, including helminths and ectoparasites [1]. T2 immune responses are activated in allergic diseases and some asthma endotypes [2]. In addition, eosinophilic airway inflammation in asthma is associated with reduced symptom control, airflow obstruction and exacerbations [3].
Real-World Impact of Mepolizumab on the Oral Corticosteroid Freedom Component of Clinical Remission in Severe Eosinophilic Asthma: International, Prospective REALITI-A Study

Feb 3, 2023 | jacionline.org | Geoffrey Chupp |Liam Heaney |N. Ireland |Rob Price

Real-World Benefits of Mepolizumab in Patients With Severe Asthma and Comorbid GERD or Anxiety/Depression: Post Hoc Analysis of REALITI-A

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