Gerard M. Loughnane

Dec 5, 2023 | biorxiv.org | Mana Biabani |Kevin Walsh |Gerard M. Loughnane |Shou-Han Zhou

AbstractADHD is a prevalent neurodevelopmental disorder associated with adverse outcomes and significant social and economic cost. However, efforts to develop a more detailed understanding of the neuropsychology of ADHD are complicated by the diversity of interindividual presentation and the inability of current clinical tests to distinguish between its sensory, attentional, arousal or motoric contributions.

Sep 13, 2023 | jneurosci.org | Daniel Pearce |Megan O’Neill |Gerard M. Loughnane |Bryce Fleming

DiscussionHere, we provide direct support for the hypothesis that build-up rates of sensory evidence accumulation are a critical neurophysiological mechanism underpinning the preservation of response speed in older adults. First, sensory evidence accumulation was not only directly related to response speed in older adults but also had an indirect impact on performance by modulating subsequent neurophysiological processes, namely, the decision criterion and the timing of the motor response.

Jul 26, 2023 | jneurosci.org | Daniel Pearce |Megan O’Neill |Gerard M. Loughnane |Bryce Fleming

AbstractOlder adults exposed to enriched environments (EE) maintain relatively higher levels of cognitive function, even in the face of compromised markers of brain health. Response speed (RS) is often used as a simple proxy to measure the preservation of global cognitive function in older adults. However, it is unknown which specific selection, decision, and/or motor processes provide the most specific indices of neurocognitive health.