Gerardo M. Oresti

Aug 1, 2024 | biorxiv.org | Elena Ramos Vásquez |María Páez |Eduardo A. Callegari |Gerardo M. Oresti

AbstractGABA B receptors (GABABRs) are heterodimeric seven-transmembrane receptors that interact with a range of proteins and form large protein complexes on cholesterol-rich membrane microdomains. As the brain ages, membrane cholesterol levels exhibit alterations, although it remains unclear how these changes impact protein-protein interactions and downstream signaling.