Gernot Beutel

3 weeks ago | nature.com | Simone Cesaro |Per Ljungman |Malgorzata Mikulska |Hans Hirsch |David Navarro |Varun Mehra | +5 more

AbstractIn the post-pandemic years, SARS-CoV-2 morbidity and mortality declined due to less pathogenic variants, active and passive immunization, and antiviral therapies. However, patients with hematological malignancies and/or undergoing hematopoietic cell transplantation (HCT) remain at increased risk for poor outcomes. Therefore, adherence to contact and droplet precautions is essential to avoid transmission, especially during epidemic waves.

Feb 25, 2025 | nature.com | Kirsi Manz |Florian H. Heidel |Steffen Koschmieder |Frank Stegelmann |Andreas Hochhaus |Haifa Kathrin Al-Ali | +3 more

AbstractMyeloproliferative neoplasms (MPN) are associated with a variety of symptoms that severely impact patients’ quality of life and ability to perform daily activities. Recent studies showed differences in the perception of physician- versus patient-reported symptom burden. However, studies directly comparing patient- and physician-reported ratings are lacking.

Nov 27, 2023 | nature.com | Evren Bayraktar |Francis Ayuk |Gernot Beutel |Olaf Penack |Thomas Luft |Gastone Castellani | +3 more

AbstractDespite advances in allogeneic hematopoietic cell transplantation, acute graft-versus-host disease (aGVHD) remains its leading complication, yet with heterogeneous outcomes. Here, we analyzed aGVHD phenotypes and clinical classifications in depth in large, multicenter cohorts involving 3019 patients and addressed prevailing gaps by developing data-driven models.