Giulia Baracchini

Jun 3, 2024 | nature.com | Giulia Baracchini |Pedro Rosa-Neto |Judes Poirier |Sylvia Villeneuve |Taylor W. Schmitz |Gary Turner | +2 more

AbstractThe neuromodulatory subcortical nuclei within the isodendritic core (IdC) are the earliest sites of tauopathy in Alzheimer’s disease (AD). They project broadly throughout the brain’s white matter. We investigated the relationship between IdC microstructure and whole-brain white matter microstructure to better understand early neuropathological changes in AD.

Sep 21, 2023 | biorxiv.org | Caitlin Walker |Linda Li |Giulia Baracchini |Jennifer Tremblay-Mercier

AbstractObjectives: Generativity, the desire and action to improve the well-being of younger generations, is positively associated with purpose in life among older adults. However, the neural basis of generativity and the neurobehavioral factors supporting the relationship between generativity and purpose in life remain unknown. This study aims to identify the functional neuroanatomy of generativity and mechanisms linking generativity with purpose in life in at-risk older adults.

Sep 18, 2023 | biorxiv.org | Caitlin Walker |Giulia Baracchini |Nagashree Thovinakere |Meishan Ai

AbstractA central question in the field of cognitive aging and behavioral neuroscience is what enables some individuals to successfully change their behavior more than others? Smoking is a significant risk factor for cognitive decline, particularly in vulnerable populations, including those who are at an elevated risk for Alzheimers disease (AD). Developing effective smoking reduction strategies is therefore a public health priority.