Giulia Moreni

Nov 5, 2024 | biorxiv.org | Licheng Zou |Giulia Moreni |Cyriel M. A. Pennartz |Jorge Mejias

AbstractThe emergence of orientation selectivity in the visual cortex is a well-known phenomenon in neuroscience, but the details of such emergence and the role of different cortical layers and cell types, particularly in rodents which lack a topographical organization of orientation-selectivity (OS) properties, are less clear.

Apr 2, 2024 | biorxiv.org | Giulia Moreni

AbstractStimulation of specific cell groups under different network regimes (e.g., spontaneous activity or sensory-evoked activity) can provide insights into the neural dynamics of cortical columns. While these protocols are challenging to perform experimentally, modelling can serve as a powerful tool for such explorations. Using detailed electrophysiological and anatomical data from mouse V1, we modeled a spiking network model of the cortical column microcircuit.

Aug 28, 2023 | biorxiv.org | Giulia Moreni |Jorge Mejias

AbstractNeural rhythms are ubiquitous in cortical recordings, but it is unclear whether they emerge due to the basic structure of cortical microcircuits, or depend on function. Using detailed electrophysiological and anatomical data of mouse V1, we explored this question by building a spiking network model of a cortical column incorporating pyramidal cells, PV, SST and VIP inhibitory interneurons, and dynamics for AMPA, GABA and NMDA receptors.