Gongqi Chen

Jul 30, 2024 | respiratory-research.biomedcentral.com | Wei Gu |Chunli Huang |Gongqi Chen |Weiqiang Kong |Lu Zhao |Guohua Zhen | +1 more

In 2004, Brinkmann and colleagues first discovered that neutrophils can release a net-like structure composed of chromatin and granule proteins in response to LPS or IL-8 stimulation. They named the net-like structure as neutrophil extracellular traps (NETs) [8]. The formation process of NETs is accompanied by breakdown of nulear and plasma membranes, and this novel form of rapid cell death was later named as neutrophil extracellular trap cell death (NETosis) [9].