Grace Holmes

Nov 4, 2023 | biorxiv.org | Grace Holmes |Sophie Ferguson |Patrick Lewis |Karen Echeverri

AbstractThe starlet sea anemone, Nematostella vectensis, is an emerging model organism with a high regenerative capacity, which was recently found to possess an orthologue to the human LRRK2 gene (NvLRRK2). The leucine rich repeat kinase 2 (LRRK2) gene, when mutated, is the most common cause of inherited Parkinsons Disease (PD). Its protein product (LRRK2) has implications in a variety of cellular processes, however, the full function of LRRK2 is not well established.