Grace Ratley

Apr 18, 2024 | nature.com | Grace Ratley

AbstractAtopic dermatitis (AD) is a chronic, inflammatory disease characterized by dry, pruritic skin. In the U.S., the prevalence of AD has increased over three-fold since the 1970s. We previously reported a geographic association between isocyanate-containing air pollution and AD as well as mechanistic data demonstrating that isocyanates induce skin dysbiosis and activate the host itch receptor TRPA1.

Aug 10, 2023 | frontiersin.org | Grace Ratley |Andac Salman |Angelo Ruggiero |Angelo V. Marzano

Introduction Despite the recent expansion of treatment options in atopic dermatitis (AD) (1), most management responsibilities fall on the patient and/or caregivers. Disease control often requires vigilance about and avoidance of common exposures, including environmental triggers, skin care products, topical medications, as well as cleansers and detergents used in the home (2). However, patients' and caregivers' considerations and concerns about trigger avoidance have not been well enumerated (1).