Graeme J. Hankey

Sep 27, 2024 | j-stroke.org | ’s Checklist |Andrew Smyth |Graeme J. Hankey |Albertino Damasceno

Stroke is a leading global cause of death and disability [1]. While dietary modification, focused on solid foods, has been a major target for prevention of stroke, daily beverage intake may represent a similarly important population-level exposure for stroke prevention [2].

Jun 18, 2024 | journals.sagepub.com | Andrew Smyth |Graeme J. Hankey |Peter Langhorne |Catriona Reddin

IntroductionStroke is a leading cause of death and disability;1 modification of common risk factors presents an attractive population-level approach for prevention. While dietary modification is a major target, daily beverage intake may represent an equally important exposure.2 In particular, coffee and tea are widely consumed (> 50% of people consuming one or both).3,4The rationale for considering tea and coffee as risk factors for stroke is based on biological and epidemiological evidence.

May 13, 2024 | onlinelibrary.wiley.com | Catriona Reddin |Wellcome Trust-HRB |Robert Murphy |Graeme J. Hankey

INTRODUCTION Blood pressure (BP) management in acute stroke has been an intensive area of interventional research; randomized controlled trials have focused on lowering elevated BP, or increasing BP in patients where hypoperfusion is suspected [1-7]. Whilst lowering BP confers a modest benefit in patients with intracerebral haemorrhage (ICH), there is no evidence to support BP lowering in acute ischaemic stroke, based on large randomized controlled trials [1, 8-10].

Mar 26, 2024 | onlinelibrary.wiley.com | Salim Yusuf |Conor Judge |John Ferguson |Graeme J. Hankey

INTRODUCTION Severe stroke is associated with increased mortality, morbidity, healthcare cost and disability-adjusted life-years [1, 2]. Identifying modifiable determinants of increased stroke severity is an important element in the effort towards reducing the global burden of stroke. Whilst symptoms of sleep disturbance have been associated with increased risk of stroke, their association with functional outcomes has not been extensively studied [3].

Aug 25, 2023 | thelancet.com | Graeme J. Hankey

1 Emberson J Lees KR Lyden P et al. Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials. Lancet. 384: 1929-1935 The second reperfusion therapy to improve outcomes in patients with proximal anterior circulation artery occlusion compared with standard care was endovascular treatment with thrombectomy within 12 h of stroke onset.