Gregory D. Longmore

Jul 3, 2023 | nature.com | Tiandao Li |Jin Zhang |Ian Hagemann |Gregory D. Longmore |Elaine R. Mardis |Christopher A. Maher | +3 more

AbstractHigh-grade serous ovarian cancer (HGSC) is the most lethal histotype of ovarian cancer and the majority of cases present with metastasis and late-stage disease. Over the last few decades, the overall survival for patients has not significantly improved, and there are limited targeted treatment options. We aimed to better characterize the distinctions between primary and metastatic tumors based on short- or long-term survival.