Gu Zhou

Nov 27, 2024 | dx.doi.org | David Schuster |Gu Zhou |Matthew Meier |Annette E Dodge

1. IntroductionClick to copy section linkSection link copied!Identifying and characterizing the mutagenic properties of environmental chemicals is an essential component of human health risk assessment. Chemicals can cause gene and/or chromosomal mutations that can drive genetic diseases, such as cancer. (1,2) Presently, genetic toxicology studies are used for hazard identification; however, there is growing acceptance that mutations are endpoints of regulatory concern.

Nov 27, 2024 | pubs.acs.org | David Schuster |Gu Zhou |Matthew Meier |Annette E Dodge

1. IntroductionClick to copy section linkSection link copied!Identifying and characterizing the mutagenic properties of environmental chemicals is an essential component of human health risk assessment. Chemicals can cause gene and/or chromosomal mutations that can drive genetic diseases, such as cancer. (1,2) Presently, genetic toxicology studies are used for hazard identification; however, there is growing acceptance that mutations are endpoints of regulatory concern.