Guanyu Huang

Sep 26, 2024 | onlinelibrary.wiley.com | Guanyu Huang |Jiajun Zhang |Yu Xu |Fei Wu

1 Introduction LACTB is a mammalian protein that contains a domain sequence similar to that of penicillin-binding proteins and β-lactamases.[1, 2] A recent study showed that LACTB acts as a tumor suppressor in breast cancer and is involved in regulating lipid metabolism.[3] After that, more scholars explored the LACTB protein and reported that it played a tumor suppressive role in several tumors, including breast cancer, hepatocellular carcinoma, colorectal cancer and glioblastoma.[3-8]...