Guilherme Nobre Nogueira

Nov 13, 2024 | onlinelibrary.wiley.com | Guilherme Nobre Nogueira

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Nov 7, 2024 | onlinelibrary.wiley.com | Guilherme Nobre Nogueira |Maria Teixeira |María Teixeira |Gunter Gerson Santos |Cauan Miranda Mateus

Recent advancements in glioma treatment are largely driven by the identification of genetic alterations, which enhance diagnostic precision and prognostic assessments, and unveil potential therapeutic targets. TERT promoter mutations, in particular, are associated with a poorer prognosis and aggressive clinical behavior. This study explores the genetic interplay between TERT and other genes (ntrk, pdl1, alk, idh, p53, egfr, her2) in brain tumors through an integrative literature review.