Güneş Taylor

2 months ago | biorxiv.org | Güneş Taylor |Emily Frost |Brendan N Crow |Arthur H Radley

AbstractPrimordial follicles are quiescent ovarian structures comprised of a single oocyte surrounded by a layer of somatic supporting pregranulosa cells. Primordial follicle activation is the first step towards oocyte maturation and, ultimately, ovulation. As the number of quiescent primordial follicles is finite, their rate of activation is a critical parameter of the duration of the female reproductive lifespan.