Guowen Wang

Nov 15, 2023 | frontiersin.org | Qi Huang |Tianyi Qiu |Guowen Wang |Yanxin Xu

1 IntroductionAs the third main malignant genitourinary tumor, renal cell carcinoma (RCC) constitutes more than 90% of all malignant kidney cancers (Oto et al., 2020). It has been estimated that there are over 400,000 new RCC cases, leading to more than 170,000 deaths annually around the world (Bray et al., 2018).

Jun 11, 2023 | mdpi.com | Jin Zhang |Xuesong Li |Yi Lu |Guowen Wang

Abstract: Simple SummaryPancreatic cancer is one of the deadliest forms of cancer, with low survival rates and limited treatment options. Anoikis resistance, or the ability of cancer cells to survive and grow in the absence of attachment to the extracellular matrix, is thought to play a critical role in pancreatic cancer progression and treatment resistance. In this study, a multi-omics approach was used to identify a set of signature genes associated with anoikis in pancreatic cancer.