Hamish Burnett

Sep 2, 2024 | inria.hal.science | John McAuley |Bertrand Servin |Hamish Burnett |Cathrine Brekke

Article Dans Une Revue Molecular Biology and Evolution Année : 2024 The genetic architecture of recombination rates is polygenic and differs between the sexes in wild house sparrows ( Passer domesticus ) hal-04681764 , version 1 (02-09-2024) John Mcauley, Bertrand Servin, Hamish Burnett, Cathrine Brekke, Lucy Peters, et al..

Jun 1, 2024 | biorxiv.org | John McAuley |Bertrand Servin |Hamish Burnett |Cathrine Brekke

AbstractMeiotic recombination through chromosomal crossing-over is a fundamental feature of sex and an important driver of genomic diversity. It ensures proper disjunction, allows increased selection responses, and prevents mutation accumulation; however, it is also mutagenic and can break up favourable haplotypes. This cost/benefit dynamic is likely to vary depending on mechanistic and evolutionary contexts, and indeed, recombination rates show huge variation in nature.

Mar 20, 2024 | biorxiv.org | John McAuley |Bertrand Servin |Hamish Burnett |Cathrine Brekke

AbstractMeiotic recombination through chromosomal crossing-over is a fundamental feature of sex and an important driver of genomic diversity. It ensures proper disjunction, allows increased selection responses, and prevents mutation accumulation; however, it is also mutagenic and can break up favourable haplotypes. This cost/benefit dynamic is likely to vary depending on mechanistic and evolutionary contexts, and indeed, recombination rates show huge variation in nature.