Hanya Ghazi

Jun 2, 2023 | mdpi.com | Vanessa Morris |Daniel Fletcher |Barbara-ann Guinn |Hanya Ghazi

Abstract:Acute myeloid leukaemia (AML) is characterized by impaired myeloid differentiation resulting in an accumulation of immature blasts in the bone marrow and peripheral blood. Although AML can occur at any age, the incidence peaks at age 65. The pathobiology of AML also varies with age with associated differences in incidence, as well as the frequency of cytogenetic change and somatic mutations.